Infarction was associated with increased RhoA/ROCK activation as shown by enhanced RhoA translocalization from the cytosol to the membrane
Infarction was associated with increased RhoA/ROCK activation as shown by enhanced RhoA translocalization from the cytosol to the membrane. performance. Fasudil showed similarly increased expression of M2 macrophages as nicorandil. The beneficial effects of nicorandil on fibroblast differentiation were blocked by adding glibenclamide. However, glibenclamide P005091 cannot abolish the attenuated fibrosis of fasudil, implying that…