W. with the condensation of palmitoyl coenzyme A (CoA) and serine by serine palmitoyltransferase (SPT), an enzyme that is negatively controlled by ORM1-like protein 3 (ORMDL3). This is followed by a series of reactions (catalysed by enzymes in reddish) leading to formation of ceramide and subsequent formation of sphingomyelin and glycosphingolipids. Ceramide can be metabolized…
66 [58C73] years). in the intensive care unit. SARS-CoV-2 positivity was confirmed by reverse transcription polymerase chain reaction (PCR) using nasopharyngeal and throat swabs. All patients were extubated after a successful spontaneous breathing trial.6 Post-extubation respiratory failure was defined as the need for reintubation or death within 96?h. Laboratory data obtained within 24?h of extubation…