7 Simulated concentration-time profiles for escalating IV bolus doses (0
7 Simulated concentration-time profiles for escalating IV bolus doses (0.1, 0.02, 0.002 nmol/kg) of darbepoetin (DA). TMDD model for just two drugs contending for the same receptor continues to be suggested. The explicit answers to the equilibrium equations make use of complicated numbers, which can’t be solved by pharmacokinetic software conveniently. Numerical bisection algorithm and…