After improve immunization for double, the DNCA/CLD-mRNA-1096-induced SARS-CoV-2 RBD-specific IgG antibody (~1:262,800) and neutralizing antibody (~1:10,591) against pseudotyped SARS-CoV-2 infection were detected in sera
After improve immunization for double, the DNCA/CLD-mRNA-1096-induced SARS-CoV-2 RBD-specific IgG antibody (~1:262,800) and neutralizing antibody (~1:10,591) against pseudotyped SARS-CoV-2 infection were detected in sera. N/P proportion was about 7: 1). The DNCA/CLD-mRNA-1096 lipoplexes had been rationally made by the mix of the lipids DNCA/CLD using the aqueous mRNA alternative under light sonication to stimulate multiple…