Mitochondrial dysfunction which caused hepatocyte apoptosis is an important element in the pathogenesis of NAFLD
Mitochondrial dysfunction which caused hepatocyte apoptosis is an important element in the pathogenesis of NAFLD. the manifestation of the anti-apoptotic protein Bcl-2, while manifestation of the pro-apoptotic protein caspase-3 was improved. When animals were treated with pharmacological inhibitors of P13K or Akt, instead of high-fat diet, a similar pattern of hepatocellular excess fat build up,…