This reveals a key functional importance of Bsn4 interaction with the C-terminus of PSMB4

This reveals a key functional importance of Bsn4 interaction with the C-terminus of PSMB4. increased proteasomal Nitisinone activity in the synaptic fractions prepared from brains of bassoon knock-out mice. Finally, increased activity of proteasome and lower expression levels of synaptic substrates of proteasome could be largely normalized upon expression of PSMB4-interacting fragments of bassoon in…