The S proteins of majority of coronaviruses are cleaved into two functional subunits, S1 and S2
The S proteins of majority of coronaviruses are cleaved into two functional subunits, S1 and S2. viral and cellular membrane, hence S protein determines the specificity of host and virulence of coronavirus [2]. Similarly, there are two non-valently associated subunits in the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein, gp120 and gp41, gp120 directs…