Treatment of acini-like structures with the -adrenergic agonists norepinephrine or isoproterenol increased granule production and -amylase staining in treated structures, demonstrating regain of protein secretion

Treatment of acini-like structures with the -adrenergic agonists norepinephrine or isoproterenol increased granule production and -amylase staining in treated structures, demonstrating regain of protein secretion. seeded on 2.5D, as well as those encapsulated in 3D HA hydrogels, self-assembled into acini-like structures and expressed functional neurotransmitter receptors. Structures in 3D hydrogels merged to form organized 50?m…