Sarewicz M, Osyczka A

Sarewicz M, Osyczka A. reduced glutathione (GSH), which are normally depleted by menadione. In addition, AIF depletion reduced the arylation of cellular proteins induced by menadione. This menadione-triggered arylation, which can be measured by a fluorescence assay, is completely suppressed by addition of exogenous glutathione or N-acetyl cysteine. Complex I inhibition by Rotenone did not…

P 0

P 0.05 was considered to indicate a statistically significant difference. Results Manifestation and purification of CDR3-LDP and CDR3-LDP-CDR3 fusion proteins As shown in Fig. purified fusion proteins were assembled with the lidamycin chromophore, and the antitumor effects were evaluated and and shown the fusion of several different CDR3 domains led to a good focusing on…