FAP, familial adenomatous polyposis; LGR5, leucine-rich repeatCcontaining G-proteinCcoupled receptor 5
FAP, familial adenomatous polyposis; LGR5, leucine-rich repeatCcontaining G-proteinCcoupled receptor 5. To assess the possibility that the observed increase in LGR5+ cell numbers in FAP crypts was because of younger age in subjects with FAP relative to healthy subjects, age was included as a covariate in the model used to test for count differences between groups.…