Recently, it has been shown that NuMA has a Hook domain and a CC1-Box-like motif, both of which interact with the effector-binding domain of DLIC (Renna et al
Recently, it has been shown that NuMA has a Hook domain and a CC1-Box-like motif, both of which interact with the effector-binding domain of DLIC (Renna et al., 2020). experiments show that cortical dynein performs bulk cytoplasmic transport by gliding microtubules along the cell cortex and through the ring canals to the oocyte. We propose…