As a result, we identified candidate chemokines by bioinformatics analysis and identified that this CXCL2 was notably up-regulated in platinum-resistant EOC

As a result, we identified candidate chemokines by bioinformatics analysis and identified that this CXCL2 was notably up-regulated in platinum-resistant EOC. a significant role in malignancy chemoresistance. This study was designed to reveal the important role of CXCL2 in platinum resistance in epithelial ovarian malignancy (EOC). Differently expressed (DE) genes were screen out based on…

The secretion and translocation of T3S effectors into the cytosol of animal or plant cells initiates a biochemical cross talk between pathogen and host (6)

The secretion and translocation of T3S effectors into the cytosol of animal or plant cells initiates a biochemical cross talk between pathogen and host (6). allows Gram-negative bacteria to produce and translocate effector proteins into the cytoplasm of host cells. While the T3S system is usually conserved among distantly related pathogens, secreted effectors are pathogen…